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Symbol
Name
ID
Hif1a
hypoxia inducible factor 1, alpha subunit
MGI:106918
Phenotype annotations related to respiratory system
Darker colors indicate more annotations

Mouse Phenotypes
increased lung weight
abnormal pulmonary alveolus epithelial cell morphology
abnormal type II pneumocyte morphology
abnormal pulmonary alveolus morphology
atelectasis
thick pulmonary interalveolar septum
abnormal tracheal ciliated epithelium morphology
abnormal tracheal cartilage morphology
respiratory distress
respiratory failure
abnormal surfactant secretion
Availability Mouse Genotype
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Col2a1-cre)1Rsjo/?  (conditional)
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0  (conditional)
Hif1atm1Rsjo/Hif1atm3Rsjo
Tg(Col2a1-cre)1Rsjo/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory